RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-208a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
PCR; immunofluorescence etc.
Target
ENDOGLIN
Pathway
NA
PubMed ID
Title
MicroRNA-208a Increases Myocardial Endoglin Expression and Myocardial Fibrosis in Acute Myocardial Infarction
Year
2015
Function
miR-208a increases endoglin expression to induce myocardial fibrosis in rats with acute myocardial infarction (AMI). Treatment with atorvastatin and valsartan can decrease myocardial fibrosis induced by AMI through attenuating miR-208a and endoglin expression.